This article is from clinical and experimental otorhinolaryngology, volume 7. Kassam tips and pearls a completely endoscopic endonasal approach provides direct access to the petrous apex for the treatment of cholesterol granulomas, petrous apicitis, and primary and metastatic neoplasms. Abstractpetrous apicitis is a rare but fatal complication of otitis media. Various surgical approaches to the petrous apex for exposure and drainage of suppurative processes are available to the otologist. Gradenigos syndrome, also called gradenigolannois syndrome, is a complication of otitis media and mastoiditis involving the apex of the petrous temporal bone.
This typically is thought to occur in pneumatized air cells. Otitis media state of the art concepts and treatment. Radiological studies for the vestibular patient ento key. Lesions of the petrous apex can be surgically treated through different surgical routes. There may be associated enhancement of the adjacent dura mater and cranial nerves due to. Which of the following findings is the typical imaging feature of petrous apex cholesteatoma. We present a rare case of petrous apicitis initiated by middle ear inflammation in a diabetic patient with. After 3 cycles, there was significant reduction in the unresected portion of the mass. Therefore, the radiologist plays a key role in the workup of patients with a petrous apex abnormality and needs to be familiar with the anatomy, anatomic variations, and imaging appearance of.
Computed tomography is generally better suited for observing airfluid levels as well as bony destruction. Acute otitis media is the second most common disease of childhood after upper respiratory infection. With contrast, cavernous sinus enhancement may also occur. This mri brain cross sectional anatomy tool is absolutely free to use. Mri and gallium spect in the diagnosis and treatment of petrous apicitis presenting as multiple cranial.
Use the mouse scroll wheel to move the images up and down alternatively use the tiny arrows on both side of the image to move the images. Magnetic resonance imaging provides information about the composition of the lesion that cannot be readily discerned on ct scans. Petrositis with bilateral abducens nerve palsies complicated. Petrositis definition of petrositis by medical dictionary. Petrous apicitis on mri keyword found websites listing. Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity. Ct, mri and gallium spect in the diagnosis and treatment. The petrous apex is the pyramidshaped anteromedial part of the petrous part of the temporal bone. Petrous apicitis can present as a headache with features of migraine, and in this case in particular, as chronic migraine without aura. A axial fast spin echo t2weighted image showing inflammation of the left mastoid, middle ear, and petrous tip curved arrow. It is oriented obliquely in the skull base and articulates with the posterior aspect of the greater wing of the sphenoid and occipital bones the lateral boundary is the inner ear, medially the petrooccipital fissure, anteriorly the petrosphenoidal fissure and petrous part of the internal. The imaging features are key, and the need for surgical intervention should be based on the correlation.
Anatomy of the petrous bone ct atlas of human anatomy using crosssectional imaging we have created an atlas of the temporal bone which is an educational tool for studying the normal anatomy of the petrous bone based on an mdct exam of the axial and coronal of the ear and petrous bone. The temporal bone and transtemporal approaches neurosurgery 2000 47 3 s211 s265 2s2. Dwi forms part of the overall imaging assessment of petrous apex disease. The diagnosis may be considered in patients with a chronic suppurative ear infection that is associated with deep ipsilateral pain. Gradenigos syndrome with abscess of the petrous apex in. The petrous apex is a pyramidshaped structure, located medial to the inner ear and the intrapetrous segment of the internal carotid artery. Cholesterol granuloma and other petrous apex lesions.
A case report of chronic migrainelike headache due to peripheral pathology. Chronic petrous apicitis with pericarotid extension into the neck in a child. Sixtysix patients treated at the house ear clinic in the last 2 decades for a lesion of the petrous apex. Clinical presentation depends on whether petrous apicitis is isolated or as is more common is a complication of acute otomastoiditis. The approach to the posterior petrous apex follows fistulous tracts in the sinodural angle, the subarcuate fossa. Septic sinus thrombosis is one of the most frequent and relevant complication of gs.
The petrous apex is the most anterior and medial portion of the temporal bone. The first step in mr imaging of the tmj is to evaluate the articular disk, or meniscus, in terms of its morphologic features and its location relative to the condyle in both closed and openmouth positions. It was first described by giuseppe gradenigo in 1904. Gradenigos syndrome secondary to chronic otitis media on a. The spread to the petrous apex is thought to arise from direct extension of advanced suppurative otitis media. Petrous apicitis can be mastoid aircell inflammation with mild petrous apicitis.
The diagnoses included temporal bone osteomyelitis 3 patients, mastoiditis 3 patients, petrous apicitis 2 patients and a combination 2 patients. Skull base inflammation r 75 3 f 65 diabetes skull base inflammation skull base inflammation r 16 4 m 81 skull base inflammation skull base inflammation l 59 5 f 61 chronic otitis media skull base inflammation l 3 6 m 83 malignant otitis externa malignant otitis externa l 12. However, the underlying pathological process apical petrositis still represents a lifethreatening condition that shall be. Petrous bone article about petrous bone by the free dictionary. Their deep location precludes direct clinical examination and easy percutaneous biopsy.
It is oriented obliquely in the skull base and articulates with the posterior aspect of the greater wing of the sphenoid and occipital bones. Gradenigos syndrome was firstly described in 1907 by giusseppe gradenigo and is defined as the clinical triad of suppurative otitis media, ipsilateral abducens nerve palsy, and pain in the distribution of the first and the second branches of the trigeminal nerve. Petrous apicitis as seen in the ct scan images below is an. Suppurative petrous apicitis is the purulent infection and. The 4 anatomic regions are the external ear, middle ear and mastoid, inner ear and the petrous apex. Incidental petrous apex findings on magnetic resonance imaging. In petrous apex air cells, the presence of which of the following accounts for the t1 hyperintensity of a cholesterol granuloma. The pathophysiological mechanisms that may underlie the. Singlephoton emission computed tomography spect may be useful when ct or mri is nondiagnostic. Mri is complementary to ct in the diagnosis of apical petrositis and provides better visualization of the intimately associated soft tissues. Because of the important neurovascular structures located inside the temporal bone, anatomical 3d knowledge is.
Feb 24, 2007 the primary infectious focus is often the tory meningitis with a propensity to the basilar cisterns middle ear cavity or paranasal sinuses with secondary often develops with cranial nerve deficits and includes spread of infection into the petrous apex and skull base tuberculous, fungal, parasitic and noninfectious leading to petrous apicitis. The measurements obtained from highresolution ct imaging of this area demonstrate a larger transarcuate space into the petrous apex when there is an air cell tract traversing the subarcuate area. Patients with petrous apicitis usually present with an acute febrile illness and some or all of the symptoms of the classic gradenigo triad ear pain, palsy of the sixth cranial nerve, and facial pain. We herein report a pediatric case of otitis media associated with gradenigo syndrome and ipsilateral sigmoidtransverse sinus thrombosis with magnetic resonance imaging findings. Magnetic resonance imaging mri of the head showed petrous apicitis with mastoiditis and abscess formation in the cerebellomedullary.
Ct is valuable in demonstrating associated cortical bone erosion. In petrous apicitis, opacification of the petrous apex is seen on ct as hypodense fluid, whereas mri will demonstrate this fluid as hypointense on t1weighted images and hyperintense on t2weighted images. Magnetic resonance imaging also detected right petrous apicitis. An accurate diagnosis is dependent on the patient s history, physical examination, and find ings on magnetic resonance imaging mri and computed tomograph y ct. It has become a very rare nosological entity after the introduction of antibiotics, so that has been defined as the forgotten syndrome. Evaluation of pneumatization of mastoid air cells using cbct.
Possible complications of petrous apicitis include meningitis, cerebral abscess formation, and venous sinus thrombosis 23. Petrous apicitis can be a serious disease and it is important for the radiologist to recognize the imaging findings and relay this information to the clinician. Osteitis developing from infected and obstructed air cells in a pneumatised petrous apex cf. Petrous apicitis is believed to occur when organisms, typically pseudomonads, become trapped within the complex air cells of the petrous apex. Mri can help demonstrate inflammation in the temporal bone petrous apicitis. The best clue to diagnosis is trabecular destruction in an opacified petrous.
If contrastenhanced ct is performed, petrous apicitis can appear as a heterogeneously enhancing infiltrating mass and may mimic neoplasm. I trained at the combined emergency medicine and pediatrics residency program at. In the past, this disease was more widespread but became much more uncommon with the introduction of antibiotics. The mr imaging findings of petrous apicitis are high signal intensity on t2weighted images, low signal intensity on t1weighted images, and contrast enhancement in a pneumatized anterior petrous. Usefulness of image guidance in the surgical treatment of. The pneumatization patterns of the roof of the parapharyngeal. The most common inflammatory condition to affect the temporal bone is acute otitis media aom. B retrofacial infralabyrinthine tract gives access to ppa and apa. Petrous definition of petrous by medical dictionary. May 27, 2015 imaging findings of developing temporal bone by nemzek et al. Temporomandibular joint tmj dysfunction is a common condition that is best evaluated with magnetic resonance mr imaging.
There may be associated enhancement of the adjacent dura mater and cranial nerves due to meningitis 2426. The mean anteriorposterior ap dimension of the intercrural space of the ssc was 4. Imaging imaging studies are invaluable in the diagnosis and management of pa. Hrct scans demonstrate soft tissue and bony changes within the petrous apex and are a fig. Mri and gallium spect in the diagnosis and treatment of petrous apicitis presenting as multiple cranial neuropathies. Richman dm, benson cb, doubilet pm, wassner aj, asch e, cherella ce, smith jr, frates mc. It articulates with the clivus and is pneumatized to a variable degree, depending on the amount of other pneumatized air cells in the temporal bone. However, they belong to the pps roof and, if present, they are potential sources of infection. Hence, image guidance could represent a useful tool when the drilling of the petrous bone must be performed, in order to reduce the surgicalrelated damage to the adjacent neurovascular structures 4, 10. Nasopharyngeal abscess and facial paralysis as complications of petrous apicitis. Ct or mr imaging demonstrates csf densityintensity lesions within enlarged, prominent meckels caves.
Although petrous apicitis was a frequent occurrence in the first half of this century, it has become an uncommon disease because of the widespread use of antibiotics for otitis media. Diagnostic imaging of temporal bone linkedin slideshare. Introduction this selfassessment module on imaging of petrous apex lesions has an educational component and a selfassessment component. Acute otitis media associated with gradenigo syndrome and. Radiographic differential diagnosis of petrous apex lesions. If this disease is allowed to progress, it will lead to intracranial infection through direct extension.
A regular followup program should be encouraged to prevent this. Gradenigo syndrome, with the classic triad of otitis, deep pain, and abducens paralysis, is rarer still. Pdf gradenigos syndrome in a patient with chronic suppurative. Abstract petrous apex abnormalities are usually incidentally detected on imaging for unrelated symptoms. Since the advent of antibiotics, the incidence of this potentially lifethreatening complication has diminished, but occasional. Petrous apicitis aka apical petrositis is a rare infection of the pneumatized petrous apex caused by the anteromedial extension of an acute otomastoiditis. Assessment of american college of radiology thyroid imaging reporting and data system tirads for pediatric thyroid nodules. With the exception of petrous apicitis and skull base osteomyelitis, all lesions of the. The educational component consists of three required articles that the participant should read. Developed by renowned radiologists in each specialty, statdx provides comprehensive decision support you can rely on apical petrositis. Gallium 67 spect as a treatment monitoring tool in.
Petrous apicitis mri keyword found websites listing. Ajnr september 1996 comparison of adult and early fetal otic capsule structures on t2weighted fast spinecho mr images. In this series of eight cases of petrous apicitis it is evident that petrositis cannot be equated with gradenigos triad otitis, abducens paralysis, and deep. Petrous apex lesions were primarily diagnosed as complications of chronic otitis media. Clinical features and choice of imaging technique patients with petrous apex lesions are often. Mancini aj, glassman rd, chang ym, burstein r, ashina s. A companion website will offer the fully searchable text and images. Petrous apicitis, also known as apical petrositis, is infection with involvement of bone at the very apex petrous. The diagnosis of mastoiditis is often made clinically, with imaging reserved for complications, such as venous sinus thrombosis, petrous apicitis, and epidural or brain abscess. One such extracranial, intratemporal complication of suppurative om is petrous apicitis pa, a medial extension of middle ear infection to the petrous apex of the temporal bone. Diagnosis is confirmed by highresolution computed tomography scan of the temporal bone and magnetic resonance imaging. Temporal bone ct and mri are the best imaging modalities for making the diagnosis.
Rami burstein harvard catalyst profiles harvard catalyst. The objective of this study was to determine if clinical presentation and management has changed over time. The parapharyngeal space pps is an inverted, coneshaped, fascial space of the suprahyoid neck that largely contains fat and is surrounded by several other important fascial spaces. Diffusionweighted mri identifies petrous apex abscess in. Skull base osteomyelitis complicated by petrous internal. Mary frates harvard catalyst profiles harvard catalyst. Oct 02, 2019 gradenigos syndrome in a patient with chronic suppurative otitis media, petrous apicitis, and meningitis. Gradenigos syndrome and otitis media pediatric em morsels.
A, in the adult, there is high signal intensity of endolymph and perilymph in membranous cochlea, and vestibule and semicircular canals are surrounded by signal. In the great majority of cases, it is capable of differentiating between petrous apicitis, cholesterol granuloma, osteomyelitis, cholesteatoma, and neoplasms such as schwannoma, meningioma, chondroma, and chordoma. Computed tomography ct scan and magnetic resonance. Treatment involves targeted intravenous antibiotics and surgical mastoidectomy with decompression and drainage of the petrous apex infection. Regarding the fact that in previous studies, the vast age range has been studied and most of them were based on gender and only ct technique was used for the purpose of evaluation of mastoid air cells pneumatization, therefore, the present study was conducted to investigate the mastoid air. Although petrous apicitis was a frequent occurrence in the first half of this century, it has become an uncommon disease because of the widespread use of. Cerebral venous sinus thrombosis is a serious neurological complication of otitis media and occurs secondary to spread of the infection to the underlying bone. Acute petrositis may appear as an expanding lesion with irregular margins. Petrous apicitis is an infectious process caused by medial extension of acute otitis media into a pneumatized petrous apex ct demonstrates opacification of petrous air cells in the early stage of the disease and bone destruction in later stages the mr imaging findings of petrous apicitis are low signal intensity on t1. Magnetic resonance imaging demonstrates findings concerning for sbo, including mastoid opacification red arrow, thickening of the eac blue arrow, and soft tissue inflammatory changes along the left tmj and infratemporal fossa with extension medially toward the nasopharynx green arrow. The lateral boundary is the inner ear, medially the petrooccipital fissure, anteriorly the petrosphenoidal fissure and petrous part of the internal carotid artery in the carotid canal. The image shows restricted diffusion in the left cerebellomedullary.
Temporal bone features diagnostic of petrous apicitis on ct scan include opacification of the mastoid air cell system, including the petrous apex. Private practice tertiary otologic referral center. Gradenigos syndrome is defined by the classic clinical triad of ear discharge, trigeminal pain, and abducens nerve palsy. Inflammation of this area may result in retroorbital or maxillary pain in the distribution of the trigeminal nerve and a palsy of the abducens nerve.
Computed tomography and magnetic resonance imaging findings article in clinical imaging 302. The transarcuate approach is a potential route to drain or biopsy a lesion in the posterior petrous apex air cells. On ct, findings of petrous apicitis include a destructive lesion with both cortical and trabecular loss in the petrous apex. Imaging of petrous bone part 1 anatomy dr mamdouh mahfouz.
Petrositis diagnosis requires imaging studies, namely, computed tomography ct, magnetic resonance imaging mri, or nuclear imaging techniques, to identify the petrous apex as the site of the inflammatory process 3. The mr imaging findings of petrous apicitis are high signal intensity on t2weighted images, low signal intensity on t1weighted images, and contrast enhancement in a pneumatized anterior petrous apex. Because the petrous apex cannot be directly visualized, imaging plays a crucial role in evaluation of lesions located there and is often critical for patient care, as treatment approaches depend. The changing face of petrous apicitisa 40year experience. Gradenigos syndrome in a patient with chronic suppurative otitis. Petrous bone is a descriptor in the national library of medicines controlled vocabulary thesaurus, mesh medical subject headings. Extension of the aom infection to the temporal bone petrous apex. The text covers all current imaging modalities, including plain film, mri, ct, ultrasound, and nuclear medicine including pet. Bilateral petrous apex cephaloceles pacs pacs are congenital or acquired herniations of the posterolateral wall of the meckels cave into the petrous apex. Epidemiology petrous apicitis is less common than it once was, on account of the widespread a. Petrous apicitis pa is a rare complication of otitis media.
Because of the important neurovascular structures located inside the temporal bone, anatomical 3d knowledge is paramount. Gradenigos syndrome with lateral venous sinus thrombosis. Magnetic resonance imaging features of gradenigos syndrome. The petrous apex may be conveniently divided into anterior and posterior portions by a line in the coronal plane through the internal auditory canal. Gradenigos syndrome gs is a rare disease characterised by the triad otitis media, pain in the region innervated by the first and the second division of trigeminal nerve and abducens nerve palsy. Surgery of petrous apex lesions requires a detailed and 3dimensional knowledge of the anatomy of the temporal bone. Petrous apicitis is a rare infection of the petrous apex of the temporal bone that occurs as a result of the spread of middle ear or mastoid infection. A glucose6phosphate dehydrogenase g6pd deficiency without anemia. Incidental petrous apex findings on magnetic resonance. Imaging modalities of the petrous bone linkedin slideshare. Singlephoton emission computed tomography and nuclear imaging studies. Petrous apicitis petrous apicitis is infection with involvement of bone at the very apex of the petrous temporal bone. Gradenigos syndrome d cases of otitis media and mastoiditis may be complicated by involvement of the petrous tip fig 6.
1543 979 621 1090 1098 70 1249 689 1576 1183 903 1587 1185 442 1213 1470 352 526 164 1686 371 282 868 1033 203 487 1365 328 6